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Enropicon (I)
Medicine

Enrofloxacin Injection

Product Information

Main Ingredient: Enropicon (I) (10%)

Pharmacologic Action

Enropicon (I) is a broad spectrum antibacterial drug in the category of fluoroquinolones for animals. It has a good effect on Escherichia coli, Salmonella, Klebsiella, Brucella, Pasteurella, Pleuropneumoniae, Erysipelas, Proteus, Serratia marcescens, Corynebacterium pyogenes, Bordetella sepsis, Staphylococcus aureus, mycoplasma, chlamydia, etc. It has a weak effect on Pseudomonas aeruginosa and Streptococcus, and a slightly weak effect on anaerobic bacteria. Enropicon (I) also has obvious post-antibacterial effect on sensitive bacteria.

The antibacterial mechanism of this product is to inhibit bacterial DNA rotation enzyme and interfere with bacterial DNA replication, transcription, repair and recombination, so that bacteria can not grow and reproduce normally and die.

Pharmacokinetics

Through intramuscular injection, this product can be rapidly and completely absorbed, and the bioavailability is 91.9% in pigs and 82% in dairy cows. It is widely distributed in animals and can enter tissues and body fluids well, except cerebrospinal fluid. The concentration of the drug in almost all tissues is higher than that in plasma. The liver metabolism is mainly to produce ciprofloxacin by removing the ethyl of 7-piperazine ring, followed by oxidation and glucuronic acid binding. The drug is mainly excreted by the kidneys (by renal tubule secretion and glomerular filtration), and 15% to 50% of the drug is excreted from the urine in its original form. The elimination half-life varies greatly in different species and different routes of administration. The elimination half-life after intramuscular injection is 5.9 hours in cows, 1.5 to 4.5 hours in sheep, and 4.6 hours in pigs.

Clinical Applications

The product is an antibacterial drug in the category of fluoroquinolones, used to treat bacterial disease and mycoplasma infection of livestock and poultry.

Intramuscular injection: at a dosage of 0.025mL per 1kg body weight of cattle and sheep.

 

Packing Specifications: 100mLx60/Carton


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