Product Features

1. Rapid Drug Effect, Efficient Penetration

Through the use of nano emulsification and microsphere sustained-release technology, 90% of the drug particles are below 5µm, and the drug can efficiently and quickly penetrate into the deep infected tissue of the breast after absorption to kill the bacteria.

2. Little Irritation

This product adopts special process treatment, and is thus non-irritating.

3. Safe to Use, Low Residue and Non-Toxic Side Effects

Animal tests show that this product has no toxicity and “mutagenesis, carcinogenesis and teratogenesis” effects.

4. Rapid Drug Effect 

Through the use of nano emulsification and microsphere slow release technology, the Product Description are stable, 90% of the drug particles are below 5µm, and the drug absorption is quick.

Notes: ND means not detected; LOQ means limit of quantitation.

The results of drug residue test showed that the residue of Ceforolin (LC) in milk after 3 days of administration was lower than MRL. According to the relevant provisions of the European Union on the calculation of MRL and withdrawal period, the withdrawal period in milk was calculated using the statistical method developed by CVMP (double unilateral 95% confidence interval). The calculation results were 3.42 days and 3.34 days, respectively, thus the withdrawal period was determined to be 4 days.

Safety Test

The clinical manifestation and local mammary symptom scores of lactating cows with 1x dose, 3x doses and 5x doses showed that no abnormality was found in the mental state, food and water intake, fecal and urinary excretion, and local mammary symptoms (swelling, flushing, fever, pain, etc.) of the cows on the 3rd day and the 5th day after continuous administration. There were no obvious adverse reactions and no animal death. Meanwhile, rectal body temperature, pulse and respiratory frequency indexes of the cows in each dose group were all within the normal range in the administration group and the control group. There were no significant differences in the above three indexes at different time points in different groups and at different time points in the same group (P>0.05). The hematological indexes of experimental group and control group were within the range of normal physiological indexes. The results showed that 5 times the recommended dose of Cefquinome Sulfate Intramammary Infusion (Lactating Cow) had no significant effect on the blood indexes of dairy cows.

Results of Skin Irritation Test

This product has no irritation to normal and damaged skin of rabbits, and the test system has comparable irritative reactions to those of bovine mucosa.

Product Specifications: 8g/Bottle x 40 Bottles/Box x 4 Boxes/Carton